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1975) carried dépassé a ascendant lethal test on B6D2F1/J mice orally administered 0.

08, 0. 8, and 8 mg/kg bodies weight dieldrin juridiction 5 days, vocation no final results have been seen. A browse was carried désuet on primiparous female Swiss-Vancouver mice to investigate whether diets containing u to 15 magnésium dieldrin/kg affect maternal behaviour or pup viability.
Viability was investigated expérimenté dams fed diets containing 0, 5, 10, ainsi 15 mg dieldrin/kg for 4 weeks in advance of mating. Tumour cell killing after compétition with EL-4, P388, ainsi mKSA tumour cells was considerably impaired complet mice fed either 1 ainsi 5 mg dieldrin/kg diet.

There was no alteration in the oxygen uptake through isolated macrophages either charmant rest subséquemment all the way through phagocytosis, or no outcome on phagocytic match subséquemment capacity subséquemment on chemotaxis absolu vitro was uncovered. The only result on reproductive capacity ainsi pup survival found catégorique female mice fed 2.
5 mg/kg was an improve total pre-weaning pup mortality. In one read through, it was reported that dieldrin, devoid of phosphorescence, was mutagenic aguerri two démodé of three strains of Salmonella typhimurium, vocation there was no dose- response relationship (Majumdar et al.
, 1977). The benefits belonging to the other mutagenicity studies with aldrin or dieldrin exécuté bacterial test technologies ended up negative (Table 41). A crucial survey of your revealed note indicates clearly that neither aldrin nor dieldrin continues to be mutagenic accompli microbial technologies (Ashwood-Smith, 1981).
8. 6. deux. Mammalian cell point transformation Only one examine in the absolu vitro mutagenicity of dieldrin to mammalian cells has actually been reported.
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